Simultaneous medullary carcinoma, papillary carcinoma and granulomatous inflammation of the thyroid
Singapore medical journal
; : e146-8, 2013.
Article
em En
| WPRIM
| ID: wpr-359067
Biblioteca responsável:
WPRO
ABSTRACT
Thyroid tumours with both papillary and medullary carcinoma features are rare and represent less than 1% of all thyroid malignancies. These tumours have a different clinical presentation and biological behaviour from tumours that have only papillary or medullary carcinoma features. The phenomenon of mixed thyroid tumours can be observed in two settings--a mixed tumour showing dual differentiation, or a collision tumour. For a precise diagnosis of this rare mixed thyroid carcinoma, fine needle aspiration cytology results should be correlated with serum calcitonin and thyroglobulin levels. The diagnosis should also be confirmed using immunocytochemistry. Surgery is the treatment of choice, and the role of postoperative radioiodine is controversial. We herein report the case of a 35-year-old man with a mixed medullary-papillary carcinoma of the thyroid, which presented with C-cell hyperplasia, granulomatous inflammation and metastasis to the cervical lymph nodes. The patient was treated with total thyroidectomy and nodal clearance. This case highlights the need for awareness of coexistent entities as they warrant separate treatments.
Texto completo:
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Índice:
WPRIM
Assunto principal:
Patologia
/
Cirurgia Geral
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Tireoidectomia
/
Neoplasias da Glândula Tireoide
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Carcinoma Papilar
/
Fotomicrografia
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Carcinoma Medular
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Inflamação
/
Metástase Linfática
/
Neoplasias Primárias Múltiplas
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Singapore medical journal
Ano de publicação:
2013
Tipo de documento:
Article