Research Progress in Genotoxic Effects of Degradation Products, Cobalt, Chromium Ions and Nanoparticles from Metal-on-metal Prostheses on Cells / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 489-492, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-359620
ABSTRACT
Cobalt or chromium alloys are the most common clinical materials of prosthesis and there have been some investigators at home and abroad have done related researches about the genotoxic effects of cobalt and chromium ions and nanoparticles. People have certain understanding about the mechanism of production of ions as well as their influence on cells. However, chromium or cobalt nanoparticles genotoxicity related research is still in its preliminary stage. In each stage, the mechanisms, from creating of the particles, through entering cells, until finally causing genotoxic, are still contained many problems to be solved. This article reviews the research progress in mechanisms of production and genotoxic effects of cobalt, chromium ions and nanoparticles.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Próteses e Implantes
/
Dano ao DNA
/
Cromo
/
Cobalto
/
Toxicidade
/
Nanopartículas
/
Íons
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2015
Tipo de documento:
Artigo
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