Bone Marrow Microenvironment and Myelodysplastic Syndromes--Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 290-294, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-360099
ABSTRACT
Myelodysplastic syndromes (MDS) are a group of bone marrow failure diseases. The bone marrow microenvironment consists of bone marrow stromal cells (BMSC), growth factors and cytokines. The BMSC supporting haemopoiesis include mesenchymal stem cells (MSC), osteoblasts, endothelial cells and macrophages, but the adipocytes play a role in the suppression of hematopoiesis. Recently more and more researches indicate that the abnormality of bone marrow microenvironment involves in the pathogenesis and progression of MDS. In this review the abnormality of MDS bone marrow microenvironment is summarized briefly.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Medula Óssea
/
Síndromes Mielodisplásicas
/
Citocinas
/
Progressão da Doença
/
Peptídeos e Proteínas de Sinalização Intercelular
/
Células-Tronco Mesenquimais
/
Microambiente Celular
/
Hematopoese
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2016
Tipo de documento:
Artigo
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