Association between gingival crevicular fluid leptin level and periodontal parameters in patients with aggressive periodontitis / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 733-736, 2014.
Article
em Zh
| WPRIM
| ID: wpr-360489
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To determine the level of leptin in gingival crevicular fluid (GCF) of patients with aggressive periodontitis (AgP) and to analyze the relationship between leptin and periodontal cilinical parameters.</p><p><b>METHODS</b>Fifty-four patients with AgP and 30 healthy controls were recruited. Detailed clinical examinations were conducted, and clinical parameters such as bleeding index (BI), probing depth (PD), attachment loss (AL) were recorded. Two teeth were selected as test teeth in each subject, one from posterior area and the other from anterior region. The level of GCF leptin was measured by enzyme linked immunosorbent assay.</p><p><b>RESULTS</b>The level of GCF leptin in AgP patients was significantly lower than that of control subjects [(16.5±4.6) ng vs.(26.0±6.0) ng, P < 0.05]. The level of GCF leptin was negatively related to BI (-0.306, P < 0.01), PD (-0.346, P < 0.01) and AL (-0.250, P < 0.01).</p><p><b>CONCLUSIONS</b>AgP patients have significantly decreased level of GCF leptin and the level of leptin was negatively related to BI, PD and AL.</p>
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Índice:
WPRIM
Assunto principal:
Periodontite Agressiva
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Ensaio de Imunoadsorção Enzimática
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Estudos de Casos e Controles
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Química
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Índice Periodontal
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Líquido do Sulco Gengival
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Leptina
/
Metabolismo
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2014
Tipo de documento:
Article