Diagnosis of intracranial malignant melanoma / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analyse the diagnosis points of intracranial malignant melanoma.</p><p><b>METHODS</b>There were ten patients with intracranial malignant melanoma (but without clear extracranial primary lesion), whose epidemiology, clinical symptom, physical sign and imaging data were analysed.</p><p><b>RESULTS</b>Most of patients were young men, The Clinical symptom or physical sign are similar to brain tumor or cerebral hemorrhage, but the course was shot, two cases of among having skin melanotic nevus. As for most of cases, CT were high density, MRI T1WI showed high signal and T2WI low signal, which often had hemorrhage. Histological examination showed all cases were malignant melanoma. Preoperative misdiagnosis was up to eight cases (80%).</p><p><b>CONCLUSIONS</b>For preoperative accurate diagnosis, this disease's epidemiology, clinical symptom, extracranial physical sign and imaging data points could be synthetical analysed.</p>