Human Prion Diseases
Journal of the Korean Medical Association
;
: 1125-1138, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-36241
ABSTRACT
Transmissible Spongiform Encephalopathy (TSE) or prion diseases are fatal neurodegenerative diseases, which are caused by transmissible abnormal prion proteins, converting the endogenous normal prion in the body to the infectious abnormal prions. The most common form of human prion diseases is Creutzfeldt - Jakob disease (CJD). Most of CJD are sporadic with unknown cause. Some familial or iatrogenic CJDs are reported in many countries, but there have been no formally reported case in Korea. Variant CJD (vCJD) is a new form of human prion disease, which revealed differentiated clinical presentations and laboratory diagnostic results. vCJD was thought to be originated from eating the beefs or other parts of bovine spongiform encephalopathy (BSE) infected cattle. The unpredictable species barriers, the underestimated distribution of prion infected tissues, the variable clinical courses, and uncertain disease progressions of many prion diseases, all made the prion related risk assessment very difficult. Korea needs our own surveillance system for various prion diseases of human and animals and to make plans for the risk assessment of the various prion disease transmissions for the minimal spread by maximizing the research capacities.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Príons
/
Encefalopatia Espongiforme Bovina
/
Doenças Priônicas
/
Medição de Risco
/
Progressão da Doença
/
Doenças Neurodegenerativas
/
Ingestão de Alimentos
/
Coreia (Geográfico)
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Animais
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of the Korean Medical Association
Ano de publicação:
2008
Tipo de documento:
Artigo
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