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A Case of Sertoli-Leydig Cell Tumor with Raised Alpha-Fetoprotein In a Patient with Thyroid Adenoma / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology ; : 1255-1260, 2004.
Artigo em Coreano | WPRIM | ID: wpr-36278
ABSTRACT
Sertoli-Leydig cell tumor (SLCT) which belong to the group of sex-cord stromal tumors is a rare ovarian tumor. It usually develops the symptom of masculinization by excessive testosterone from the Leydig cell. In most cases, SLCTs are unilaterally localized (97-98%) and prognosis prove generally favorable with 5-year survival rate (79-90%). Recurrence is rare after a complete resection as well. Rare SLCTs secrete the alpha-fetoprotein (AFP). There is a increasing tendency for the SLCTs that have heterologous elements and low differentiation to secrete the AFP, which is useful in diagnosis of recurrence. The association of a thyroid adenoma and a SLCT has been described rarely. The relation between these two tumors has been suggested on the basis of a relatively high incidence of thyroid adenomas in the presence of such an uncommon ovarian neoplasm. It seems likely that this tumor complex is genetically determined by the aspect of familial neoplastic syndromes. We experienced a case of Sertoli-Leydig cell tumor with AFP-producing Sertoli cells in a 33-years old woman who has past history of thyroid adenoma, amenorrhea and a huge abdominal mass. Therefore, we present it with a brief review of literature.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Ovarianas / Prognóstico / Recidiva / Células de Sertoli / Testosterona / Glândula Tireoide / Neoplasias da Glândula Tireoide / Alfa-Fetoproteínas / Incidência / Taxa de Sobrevida Tipo de estudo: Estudo diagnóstico / Estudo de incidência / Estudo prognóstico Limite: Adulto / Feminino / Humanos Idioma: Coreano Revista: Korean Journal of Obstetrics and Gynecology Ano de publicação: 2004 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Ovarianas / Prognóstico / Recidiva / Células de Sertoli / Testosterona / Glândula Tireoide / Neoplasias da Glândula Tireoide / Alfa-Fetoproteínas / Incidência / Taxa de Sobrevida Tipo de estudo: Estudo diagnóstico / Estudo de incidência / Estudo prognóstico Limite: Adulto / Feminino / Humanos Idioma: Coreano Revista: Korean Journal of Obstetrics and Gynecology Ano de publicação: 2004 Tipo de documento: Artigo