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Excellent Hemostatic Effects of Aprotinin in Coronary Artery Bypass Surgery and Some Problems / 日本心臓血管外科学会雑誌
Japanese Journal of Cardiovascular Surgery ; : 404-408, 1994.
Artigo em Japonês | WPRIM | ID: wpr-366078
ABSTRACT
To determine the hemostatic effets of aprotinin in coronary artery bypass surgery, a prospective study was performed. Thirty four patients (group A) who received aprotinin (2×10<sup>6</sup> unit) in the cardiopulmonary circuit were compared with 31 control patients (group C) who did not. Activated clotting time was measured in group A for 60 minutes during cardiopulmonary bypass, but no significant difference was observed in the platelet counts of the two groups. Intraoperative blood loss was 366ml in group A compared with 514ml in group C, and postoperative blood loss was 354ml versus 570ml, respectively (<i>p</i><0.05). Total blood loss was significantly reduced in group A by 34% compared with group C (720ml versus 1, 084ml, <i>p</i><0.05). There was no difference in incidence of perioperative myocardial damage. It seems necessary to investigate the complications of the hemostatic effects of aprotinin and it effects on graft patency.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional Idioma: Japonês Revista: Japanese Journal of Cardiovascular Surgery Ano de publicação: 1994 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional Idioma: Japonês Revista: Japanese Journal of Cardiovascular Surgery Ano de publicação: 1994 Tipo de documento: Artigo