A Case of Cyclophosphamide-induced Hemorrhagic Cystitis Successfully Treated with Traditional Chinese Medicine / 日本東洋医学雑誌

ABSTRACT

A case of cyclophosphamide-induced hemorrhagic cystitis was successfully treated with traditional Chinese medicine after various forms of urological treatment had failed. A 42-year-old female patient who had been receiving cyclophosphamide for about nine years (total dose of 104g) visited our department for severe hematuria. Since various kinds of urological treatment failed to stop gross hematuria, traditional Chinese medicine was tried. The patient was diagnosed as having underlying Yin-deficiency of the kidney and had developed “asthenic heat-syndrome”. In addition, she had “deficiency of vital energy and blood” and “deficiency of vital energy and blood stagnation” as a result of long-term massive hemorrhage. The treatment focused on “tonifying the deficiency of kidney Yin”, and “ treatment for cooling the blood” and “tonifying vital energy and activating blood”were also performed. Urinary findings became normal three months later, and she has remained uneventful for 12 months thereafter.