The Therapeutic Effect of Unsei-in on Facial Redness (Inflammatory Congestion) in Atopic Dermatitis. A Clinical Study of 20 Cases / 日本東洋医学雑誌

ABSTRACT

The effectiveness of Kampo therapy for facial redness was studied in 20 cases of atopic dermatitis, using the Kampo extract Unsei-in (EK-57, etc.), which is known to have antiinflammatory and anti-allergic activities. Unsei-in was used without other Kampo extracts in 10 cases. Of these, marked improvement was observed in one case (10%) and improvement in two cases (20%), all of which improved within two weeks. Five cases did not respond to therapy, and the redness worsened in two cases. In ten other cases Unsei-in was used in conjunction with other Kampo extracts. Of these, improvement was observed in three cases (30%). Adverse reactions such as redness over the entire body (one case; 5%) and gastric pain (one case; 5%) were also observed. Despite these reactions, Unsei-in was shown to be useful in the treatment of facial redness associated with atopic dermititis.