The Effects of Kami-kihi-to(Jia-Wei-Gui-Pi-Tang) on Hematological Findings and Systemic States in a Patient with Hemochromatosis after Blood Traensfusions for Myelodysplastic Syndrome / 日本東洋医学雑誌

ABSTRACT

Myelodysplastic syndrome (MDS) is very difficult to treat, especially in case requiring blood transfusion therapy. Kami-kihi-to (Jia-Wei-Gui-Pi-Tang) was reported to have had a hematological effect on a case of idiopathic thrombocytopenic purpura. As it is well known that Kami-kihi-to improves anemia, we tried Kami-kihi-to for a case of MDS needing frequent blood transfusion, and analyzed its hematological and systemic effects. A 74-year-old man with MDS suffered from appetite loss and general fatigue-probably due to hemochromatosis with liver dysfunction after chemotherapy with prednisolone, metenolone and blood transfusion-for about eight years. Kami-kihi-to was administered to the patient, and two months later, his leukocyte and platelet count of peripheral blood increased, while the red cell count did not increase. Bone marrow findings remained constant before and after Kami-kihi-to therapy. The appetite loss and general fatigue improved after six weeks of this treatment. Kami-kihi-to is an appropriate treatment option for MDS with hemochromatosis that induces appetite loss or general fatigue.