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Diagnosis and Prediction of Clinical Outcomes in Patients with Acute Lacunar Infarction: Usefulness of Perfusion MR Imaging
Journal of the Korean Radiological Society ; : 431-436, 2002.
Artigo em Coreano | WPRIM | ID: wpr-36874
ABSTRACT

PURPOSE:

To correlate the findings of perfusion-weighted imaging (PWI) with clinical outcomes in patients with acute lacunar infarction. MATERIALS AND

METHODS:

Eleven patients (7 males and 4 females) with acute lacunar infarction who were examined within 50 (mean, 29) hours of the onset of symptoms underwent conventional MRI, diffusion-weighted imaging (DWI) and PWI. Gadolinium (0.2 mmol/kg) was injected at a rate of 2 ml/sec, and PWI was performed using a gradient-echo EPI pulse sequence and the following parameters TR/TE, 2000/60; flip angle, 90 degree; matrix size, 128X128. Relative cerebral blood volume (rCBV) maps were derived from gadolinium bolus perfusion-weighted images where rCBV ratios between infarcted areas were detected by DWI, and contralateral control areas were obtained. In each case, the resulting rCBV ratio at a lesion site was compared with the clinical outcome determined on the basis of the difference between National Institute Health Stroke Scale (NIHSS) scores at admission and discharge.

RESULTS:

With the aid of the time-intensity curve obtained at PWI, the rCBV maps revealed a hypoperfused area in 10 of 11 patients, and there was positive correlation (r=0.81) with clinical outcome.

CONCLUSION:

Although PWI has a lower detection rate than DWI, it may be a useful modality for helping determine prognosis in cases of acute lacunar infarction.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Perfusão / Prognóstico / Volume Sanguíneo / Imageamento por Ressonância Magnética / Acidente Vascular Cerebral / Diagnóstico / Acidente Vascular Cerebral Lacunar / Gadolínio Tipo de estudo: Estudo diagnóstico / Estudo prognóstico Limite: Humanos / Masculino Idioma: Coreano Revista: Journal of the Korean Radiological Society Ano de publicação: 2002 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Perfusão / Prognóstico / Volume Sanguíneo / Imageamento por Ressonância Magnética / Acidente Vascular Cerebral / Diagnóstico / Acidente Vascular Cerebral Lacunar / Gadolínio Tipo de estudo: Estudo diagnóstico / Estudo prognóstico Limite: Humanos / Masculino Idioma: Coreano Revista: Journal of the Korean Radiological Society Ano de publicação: 2002 Tipo de documento: Artigo