Next Generation DNA Sequencing and Its Application in Clinical Medicine / 대한주산의학회잡지
Korean Journal of Perinatology
;
: 133-139, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-36941
ABSTRACT
Watson and Crick published a paper on the double helical structure of DNA in Nature in April 25, 1953. The human genome is contained in the 23 pairs of chromosomes and in the mitochondrial DNA of each cell. The Human Genome Project was launched in 1990 under the direction of Watson and concluded in 2003, on the 50th anniversary of Watson and Crick paper. Over 6 billion of nucleotides of genetic codes are in single cells. There are 23,000 protein coding genes and the remainder are non-coding DNA, regulatory DNA. Since the completion of Human Genome Project, these huge genomic information has been translated into clinically usable medical information. With the advent of massively parallel DNA sequencing, known as next generation DNA sequencing, the cost and turn-around time were significantly reduced so that the era of Whole Genome Sequencing entered into hospitals and medical clinics. On June 16, 2014 American Society of Human Genetics revised its mission statement as follows. "Our mission is to advance human genetics in science, health and society through research, education and advocacy". Finally medical genetics nestled its roots in the midst of genetics and genomics.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
DNA
/
DNA Mitocondrial
/
Medicina Clínica
/
Genoma Humano
/
Projeto Genoma Humano
/
Genoma
/
Análise de Sequência de DNA
/
Genômica
/
Educação
/
Codificação Clínica
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Perinatology
Ano de publicação:
2014
Tipo de documento:
Artigo
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