Electro-acupuncture Analgesia After Neonatal and Adult Capsaicin Treatment / 全日本鍼灸学会雑誌

ABSTRACT

Effects of capsaicin (CAP) treatment on electro-acupuncture (EA) analgesia were studied by examining, threshold of rats treated CAP in their naonatal and adult periods. Pain threshold of animals were measured as the latency until the occurrence of the hind paw withdrawal in response to heat noxious stimuli by using a hot-plate (HP) method. In control rats, application of EA to the right forepawLI-10, 11), increase the latency to about 160% of the control level (befor the EA application), where as in rats treated with CAP in both neonatal and adult periods, EA application hardly affected the latency.<br>There results suggests that treatment with CAP in both neonatal and adult period abolishes the EA analgesia in rats.