Epidemiological Study on Skin Hazards Due to Dithiocarbamate Fungicides / 日本農村医学会雑誌

ABSTRACT

An epidemiolgical survey as well as a case study on the skin hazards due to dithiocarbamate fungicides, such as Maneb and Manzeb (Mancozeb), were carried out. The results were summarized as follows;<BR>1. From the epidemiological survey, the incidence rate of skin lesions due to the dithiocarbamates in three areas were 42.4%(39/92), 43.3%(113/261) and 27.6%(42/151), respectively.<BR>2. The skin lesions appeared generally in face, hands and nape of neck and collar areas and also in covered areas of the body such as breast, back and so forth.<BR>3. By patch testing with a dithiocarbamate “Maneb” the positive reactions in 40 cases tested were observed in 18%, 23% and 15% of the subject with 0.1%, 0.05% and 0.025% preparations, respectively.<BR>The results suggested that allergic type of contact dermatitis is involved in the skin hazard due to the dithiocarbamate fungicides.