Epidemiological study on the relation of serum lactate dehydrogenase (LDH) isozymes and activity to protein intake in man / 日本農村医学会雑誌

ABSTRACT

This paper reports the changes in the activity and isozyme pattern of serum LDH in healthy young men given a low protein diet (0.73-0.75/kg body weight; 40-50g/day) for 21 days.<BR>Serum total LDH activity showed no significant change in eight healthy young volunteers who received low protein diet for 21 days. However, the percentages of LDH-5 and LDH-4 increased significantly (P<0.01) from basal levels of 5.9±2.3 and 7.1±1.4 to 10.6±2.9% and 10.1±0.9%, respectively on day 14.<BR>These results suggest that measurements of the percentages of LDH-4 and LDH-5 isozymes can be used to evaluate the protein intake, but serum LDH activity cannot be used as an index of nutrition.