A successful treatment using gabapentin against hot flashes due to LH-RH agonist in a patient with advanced prostate cancer
Palliative Care Research
;
: 334-338, 2009.
Artigo
em Japonês
| WPRIM
| ID: wpr-374666
ABSTRACT
<b>Purpose</b> To report a case of successful treatment using gabapentin against hot flashes due to LH-RH agonist in a patient with advanced prostate cancer. <b>Case summary</b> A male patient in his seventies with advanced prostate cancer had hot flashes due to LH-RH agonist therapy. The patient began to notice hot flashes within a few months after starting hormone treatment. Oral gabapentin was administered at a starting dose of 400mg/day and was gradually escalated to 1,200mg/day. Within 7 days of administration, the patient achieved a partial improvement of his symptoms. After 17 days of gabapentin therapy, the hot flashes significantly improved. While the patient was taking a maintenance dose of 1,200mg/day, he remained to be asymptomatic. <b>Conclusion</b> There are only a few reports (none in Japan) that show effectiveness of gabapentin against hot flashes due to hormone treatment in male patients with prostate cancer. Although the mechanism of the hot flash-relieving effect of gabapentin is not fully understood, this case report indicates that gabapentin may help treating patients suffering from intractable hot flashes. Palliat Care Res 2009; 4(2) 334-338
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Japonês
Revista:
Palliative Care Research
Ano de publicação:
2009
Tipo de documento:
Artigo
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