First Susceptibility Testing of <i>Mycobacterium tuberculosis</i> for Second-line Anti-tuberculosis Drugs in Ghana
Tropical Medicine and Health
;
: 53-55, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-375180
ABSTRACT
We performed drug susceptibility testing on first- and second-line drugs in <i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>) for the first time in Ghana to obtain preliminary data on drug-resistant tuberculosis. Of 21 isolates (4 new cases and 17 treated cases), 5 (23.8%) were multi-drug resistant tuberculosis (MDR-TB) and 19 (90.5%) were resistant to at least one drug, but no extensively drug-resistant TB (XDR-TB) was identified. Since the target patients were Category II, IV or smear positive at follow-up microscopy, it is understandable that there were many drug-resistant TB cases. Six isolates were resistant to one or two second-line drugs, but the second-line drugs were not approved in Ghana. It is considered that the bacilli were imported from abroad. Preventing the import of drug-resistant TB bacilli is probably one of best ways to control TB in Ghana.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Tropical Medicine and Health
Ano de publicação:
2014
Tipo de documento:
Artigo
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