Inhibitory Activity of Porcine Placenta Extracts on Angiotensin I Converting Enzyme / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
;
: 35-38, 2009.
Artigo
em Japonês
| WPRIM
| ID: wpr-376470
ABSTRACT
<i>Objective</i> Angiotensin I Converting Enzyme was used to study the inhibitory activity of porcine placenta extracts.<br> <i>Methods</i> ACE was derived from rabbit lung. Bz-Gly-His-Leu was used as a substrate. Production of hippuric acid was measured by HPLC.<br> <i>Result</i> ACE inhibitory activity was measured in a two-fold dilution of porcine placenta extracts. The IC<sub>50</sub> of porcine placenta extracts was 95.7 μg. The results of a Lineweaver-Burk plot suggested that porcine placenta extracts exhibited a competitive inhibition.<br> <i>Conclusion</i> In this paper, we found that porcine placenta extracts had an anti-ACE activity.<br>
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Japonês
Revista:
Japanese Journal of Complementary and Alternative Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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