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Limited Role of Bone Marrow Aspiration and Biopsy in the Initial Staging Work-up of Gastric Mucosa-Associated Lymphoid Tissue Lymphoma in Korea
Gut and Liver ; : 637-642, 2014.
Artigo em Inglês | WPRIM | ID: wpr-37652
ABSTRACT
BACKGROUND/

AIMS:

The aim of this study was to investigate the frequency of disseminated gastric mucosa-associated lymphoid tissue (MALT) lymphoma and the role of bone marrow study in the initial staging work-up.

METHODS:

A total of 194 patients with gastric MALT lymphoma was enrolled. The incidence of disseminated disease was evaluated in the initial staging work-up. The demographic data and tumor characteristics were compared according to Helicobacter pylori infection status.

RESULTS:

Localized disease of Lugano stage I accounted for 97.4% of the enrolled cases. Abdominal computed tomography revealed abdominal lymph node metastasis in five patients (2.6%). Bone marrow (BM) involvement was found in only one patient without H. pylori infection (0.5%). No patient showed positive findings on chest computed tomography or positron emission tomography. H. pylori-negative cases showed a significantly higher frequency of advanced-stage disease than H. pylori-positive cases (10.0% vs 0.6%). In patients achieving complete remission, no extragastric recurrence occurred during follow-up.

CONCLUSIONS:

The incidence of disseminated disease, including BM involvement, was very low in Korean gastric MALT lymphoma patients. It might be beneficial to perform BM aspiration and biopsy as a part of staging work-up only in patients with risk factors for advanced disease such as H. pylori negativity.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Gástricas / Medula Óssea / Exame de Medula Óssea / Radiografia Abdominal / Tomografia Computadorizada por Raios X / Estudos Retrospectivos / Estudos de Coortes / Infecções por Helicobacter / Linfoma de Zona Marginal Tipo Células B / Abdome Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Fatores de risco Limite: Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Inglês Revista: Gut and Liver Ano de publicação: 2014 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Gástricas / Medula Óssea / Exame de Medula Óssea / Radiografia Abdominal / Tomografia Computadorizada por Raios X / Estudos Retrospectivos / Estudos de Coortes / Infecções por Helicobacter / Linfoma de Zona Marginal Tipo Células B / Abdome Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Fatores de risco Limite: Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Inglês Revista: Gut and Liver Ano de publicação: 2014 Tipo de documento: Artigo