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Relationship between environmental exposures,genetic polymorphism of NAT2 and colorectal cancer / 肿瘤研究与临床
Cancer Research and Clinic ; (6): 89-91, 2010.
Artigo em Chinês | WPRIM | ID: wpr-379963
ABSTRACT
Objective To explore the relationship between NAT2 genetic polymorphism and the risk of colorectal cancer. Methods A hospital-based case-control study was conducted and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used to detect its genotypes.Results The frequency of NAT2 slow genotype was 19.58% in cases with colorectal cancer compared.with increased the risk for developing colorectal cancer and their OR were 2.16(95% CI1.31~3.54).Conclusion The results suggest that NAT2 genetic polymorphism is associated with colorectal canoer susceptibility.People with NAT2 slow genotype have higher coloreetal cancer risk.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional / Fatores de risco Idioma: Chinês Revista: Cancer Research and Clinic Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo observacional / Fatores de risco Idioma: Chinês Revista: Cancer Research and Clinic Ano de publicação: 2010 Tipo de documento: Artigo