Application of hIL-24 gene in combination therapies of tumors / 肿瘤研究与临床

ABSTRACT

The human interleukin-24 gene (hIL-24),alse referred to as melanoma differentiation associated gene-7 (MDA-7), is a novel cancer-selective apoptosis-inducing eytokine gene with broadspectrum antitumor activity. Multiple data have demonstrated that treatment of tumors with a combination of IL-24 and other strategies such as drug therapy, radiation, dual gene therapy and so on, caused synergistic antitumor effects. These results will provide a impetus for further combination therapy in various tumors.