The relationship between inflammation of blood vessels and microcirculation disturbance in liver of patients with chronic hepatitis B / 中国基层医药

ABSTRACT

Objective To study the effects of inflammation of blood vessels to microcirculation disturbance in liver of patients with chronic hepatitis B(CHB). Methods188 cases of hepatic tissue with CHB were observed by light microscope and electronmicroscope.They were graded according to the inflammation of blood vessels in liver,and to discuss the relationship between the inflammation of blood vessel and microcirculation disturbance. ResultsAccording to the inflammation of blood vessels in liver,188 cases of CHB were divided to 3 grades,67 cases in grade 1,89 cases in grade 2 and 32 cases in grade 3.The rate of hepatic sinusoidal stenosis,hepatic sinusoidal blockage,the formation of microthrombus,decreased sizes and reduced numbers of sinusoidal endothelial cells' penestrate,the formation of collagen in Disse's spaces and the formation of basilar membrane increased along with the aggravation of inflammation of hepatic blood vessels. ConclusionInflammation of hepatic blood vessels was an important factor on microcirculation disturbance in liver of patients with CHB.It should be done something to improve the microcirculation,and decrease inflammation at the same time.