The study of serum TWEAK and survivn in rheumatoid arthritis / 中华风湿病学杂志
Chinese Journal of Rheumatology
;
(12): 759-761, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-385709
ABSTRACT
Objective To measure the serum levels of TWEAK and survivin in rheumatoid arthritis (RA)patients and explore their clinical value. Methods The serum levels of TWEAK and survivin were measured by ELISA methods in 61 patients with RA and 35 healthy controls. The function stage, X-ray stage,and serum levels of ESR, RF and CRP were measured at the same time. Results There was no significant difference between the serum levels of TWEAK in patients with RA[(479±381)pg/ml]and control[(421±87 pg/ml]. The serum level of survivn in patients with RA[(159±82)pg/ml]was increased significantly than that of the controls[(119±24)pg/ml]and were associated with X-ray stage. Conclusion We need further research to explore the relationship between TWEAK and RA. The serum level of survivin is associated with chronic erosive RA and maybe a target for new therapeutic approach of RA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Rheumatology
Ano de publicação:
2010
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS