Livin and malignant tumor / 国际肿瘤学杂志

ABSTRACT

The inhibitor of apoptosis proteins (IAPs) are importants factors of cell apoptosis inhibitors that are closely related to tumorigenesis and tumor development. Livin is selectively expressed in most common human malignant neoplasms. It is demonstrated that Livin may play an important role in tumorigenesis. To research the biological characteristics and the role of Livin is significant to tumor development and progression, chemoresistance ,tumor therapy and prognosis. In recent years,immunotherapy and gene therapy for the targeting of Livin have become a spot research, which provid new strategy and direction for tumor therapy.