Medical treatment of advanced esophageal cancer / 国际肿瘤学杂志

ABSTRACT

Cisplatin in combination with fluorouracil still is considered as the basic therapeutic scheme for advanced esophageal cancer. New cytotoxic drugs, such as taxanes and topoisomerase inhibitor etc, and new regimens are focus researches for medical treatment. Intravenous fluorouracil can be replaced by oral fluorouracil derivative, and cisplatin can be replaced by oxaliplatin in the regimens of contained cisplatin and fluorouracil for advanced esophageal cancer. Patients with advanced esophageal cancer are now offered seconded line treatment, and the number of research protocols is increasing. Molecule targeted therapy as a promising treatment will provide more and better options for patients.