Thoracic radiotherapy in limited-stage small cell lung cancer / 国际肿瘤学杂志

ABSTRACT

The effective therapy of limited stage-small cell lung cancer( LS-SCLC) is combined chemotherapy and thoracic radiotherapy(TRT). Early thoracic irradiation is better than later one. Start of any treatment and end of radiotherapy less than 30 days is associated with improved survival in LS-SCLC patients. Concurrent chemoradiotherapy results in longer survival time than sequential and alternating chemoradiotherapy. There are no clear answers on optimal irradiation dose. Hyperfractinated irradiation may have therapeutic benefit compared with conventional irradiation.