A Case of Papillary Thyroid Carcinoma Combined with Multiple Endocrine Neoplasia Type 2A / 대한내분비학회지
Journal of Korean Society of Endocrinology
;
: 730-738, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-38857
ABSTRACT
Multiple endocrine neoplasia (MEN) type 2A is a syndrome of medullary thyroid carcinomas, pheochromocytomas and parathyroid hyperplasia. The simultaneous occurrence of medullary, and papillary, thyroid carcinomas is rare because they are derived from, apparently, different germ layers, the former from the neuroectoderm and the latter from the endoderm. We report a case of a papillary thyroid carcinoma, combined with a medullary thyroid carcinoma, in a patient with MEN type 2A. Molecular genetic studies for screening a RET proto-oncogene mutation revealed a point mutation in codon 631 on chromosome 10, which is reported as highly uncommon in MEN type 2A.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Feocromocitoma
/
Glândula Tireoide
/
Cromossomos Humanos Par 10
/
Proto-Oncogenes
/
Códon
/
Neoplasia Endócrina Múltipla
/
Neoplasias da Glândula Tireoide
/
Programas de Rastreamento
/
Mutação Puntual
/
Neoplasia Endócrina Múltipla Tipo 2a
Tipo de estudo:
Estudo de rastreamento
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
2002
Tipo de documento:
Artigo
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