Recent Advances in the Development of Experimental Animal Models Mimicking Human Aortic Aneurysms
Vascular Specialist International
;
: 1-10, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-38888
ABSTRACT
Aortic aneurysm is a common and life-threatening disease that can cause death from rupture. Current therapeutic options are limited to surgical or endovascular procedures because no pharmacological approaches have been proven to decrease the chance of expansion or rupture. The best approach to the management of aortic aneurysm would be the understanding and prevention of the processes involved in disease occurrence, progression, and rupture. There is a need for animal models that can reproduce the pathophysiological features of human aortic aneurysm, and several such models have been studied. This review will emphasize recent advances in animal models used in the determination of mechanisms and treatments of aortic aneurysms.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aorta
/
Aneurisma Aórtico
/
Ruptura
/
Modelos Animais
/
Procedimentos Endovasculares
/
Aneurisma
Limite:
Humanos
Idioma:
Inglês
Revista:
Vascular Specialist International
Ano de publicação:
2015
Tipo de documento:
Artigo
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