Progress in relationship between inhibitor of apoptosis protein Livin and tumors / 国际儿科学杂志

ABSTRACT

Livin is a newly discovered member of the inhibitor of apoptosis protein family. Its antd-apoptosis function is mainly by inhibiting of casepases protein. So far, the over expression of Iivin has been detected in many malignant tumors.Research showed that Iivin may play a role in the progress of carcinogenesis of tumors and also be related with the resistance and the prognosis.Livin may serve as a new target for tumros diagnosis and treatment.In this review, we will summarize the new development in the relationship of Iivin and tumors in recent years.