Regional myocardial function and genetic bases in patients with hypertrophic cardiomyopathy / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 297-300, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-390075
ABSTRACT
Hypertrophic cardiomypathy is a genetically heterogeneous cardiac disease transmitted as an autosomal dominant trait,mostly caused by mutant of myofribrilla gene such as β-MHC, MYBPC3, cTnT.cTnI,cTnC, a-Tm and some other gene which coding non-myofribrilla. Different mutant caused different regional myocardium systolic or diastole function, which involve in dysfunction of systolic and diastolic deformation, increase of the sensitive of Ca2+ . This review summarizes the most common gene mutations in hypertrophic cardiomypathy and explains the changes of myocardial functions.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2010
Tipo de documento:
Artigo
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