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Progress in immunopathogenesis of Henoch-Sch(o)nlein purpura / 国际儿科学杂志
International Journal of Pediatrics ; (6): 183-185, 2010.
Artigo em Chinês | WPRIM | ID: wpr-390408
ABSTRACT
Henoch-Schnlein purpura(HSP) is a common autoimmune small vessel vasculitis that primarily affects children.Although the pathogenesis of HSP is unknown,there are tantalizing clues on the immune abnormalities mediated by IgA,which mainly affects the vessels of the skin,gastrointestinal tract and kidneys.The reasons of deposition maybe involve in the increases of serum IgA,the abnormalities of IgA-specific autoantibodies,structures and acceptors of IgA1,complements,and so on,which mediates the abnormal expressions of adhesion molecules and cytokines.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Pediatrics Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Pediatrics Ano de publicação: 2010 Tipo de documento: Artigo