Ferritin and hemoglobin in primary restless legs syndrome / 中国综合临床

ABSTRACT

Objective To investigate the association of serum ferritin and hemoglobin with the pathogenesis of primary restless legs syndrome(RLS). Methods Thirty-five patients with primary restless legs syndrome and twenty insomnia controls were included in this study. The level of serum ferritin and hemoglobin were measured, and the data have been analyzed using t-test. Results The level of serum ferritin in the primary RLS patients (89.77μg/L (SD48.52)) was significantly lower than in the contruls (123.36 μg/L (SD35.06)) (t=-2.713,P <0.01), whereas the level of hemoglobin have no statistical difference between the RLS group (142.77 g/L (SD 11.79)) and the control group (139.05 g/L (SD 12.33)) (t = 1.108, P > 0.05). Conclu-sions The decrease of serum ferritin may be a risk factor of primary restless legs syndrome, but the level of hemo-globin is not associated with primary restless legs syndrome.