Psychological assessment of secondarily generalized tonic clonic seizures / 中国医师进修杂志

ABSTRACT

Objective To investigate the neuropsychological characteristics of secondarily generalized tonic clonic seizures (SGTCS). Methods Twenty patients of SGTCS were divided into higher SGTCS group (the times of SGTCS ≥ 20,10 cases) and lower SGTCS group (the times of SGTCS < 20,10 cases). Investigated the tests of verbal intelligence quotient (VIQ), procedure intelligence quotient (PIQ) and full-scale intelligence quotient(FIQ), as well as cognitive test, BCRT-reaction time, CVST-reaction time and the deterioration scores. Results The VIQ, PIQ, FIQ and cognitive test of higher SGTCS group were significantly lower than those in lower SGTCS group[(94.9 ± 20.9) scores vs (116.0 ± 17.8) scores, (95.3 ±16.8) scores vs(117.8 ± 12.4) scores, (94.3 ±20.6) scores vs (118.0±12.8) scores, (14.1±4.9) scores vs (19.8 ± 2.1)scores] (P < 0.05 or < 0.01), and the outcomes of CYST-reaction time and the deterioration scores were significantly higher than those in lower SGTCS group [(16.6 ± 5.1) s vs (11.9 ± 2.0) s, (3.1 ± 1.4) scores vs(1.6 ± 1.1) scores](P < 0.05). Conclusion Intellectual and information gathering capability of SGTCS were deteriorated with the degree of disease worsened.