Thrombolytic strategies for acute ischemic stroke / 国际脑血管病杂志

ABSTRACT

Thrombolytic therapy is a main treatment method for ischemic stroke.Intravenous recombinant tissue-type plasminogen activator (rtPA) is the only FDA-approved therapy for acute stroke; however,its clinical application has been limited because the narrow therapeutic time window and the presence of the risk of hemorrhagic complication.In order solve these problems,a large number of clinical trials have started to focus on the studies of intra-arterial thrombolysis,mechanical thrombolysis and sonothrombolysis.