Research progress on photodynamic therapy in dentistry / 国际生物医学工程杂志

ABSTRACT

As a new technique, photedynamic therapy was introduced in the end of 1970s and has been put into clinical application from experimental tests in recent years. Its mechanisms was established on the basis that a series of special typed cells and tissues could selectively absorb photosensitive drugs and generate photore-sponsive effects by light irradiation of definite wavelengths. Currently, the photodynamic theraputics is applied mainly in non surgical treatment of tumor betided in body superfacial and hollow viscus. Its application area has been expanded unceasingly in modern clinic due to the discovery of the selective aggregation of photoresponsive drugs to many pathological tissues and pathogenic microorganisms other than tumors, and the development of new photoresensitizer. In this paper, review is given on the effect mechanisms, the light sources and photosensitizer, as well as the application of photodynamic treatment of tumors in head and neck and its treatments of mucosal dis-ease and oral pathogenic microorganism infected diseases.