Clinical analysis of 53 cases of cerebral venous sinus thrombosis / 中国综合临床

ABSTRACT

Objective To analyze the clinical characteristics of cerebral venous sinus thrombosis(CVST)and evaluate the diagnosis and treatment.Methods All the medical records,including age,mode of onset,clinical manifestations,findings of neuro-imaging and prognosis were analyzed.retrospectively in 53 cases with CVST from August 2003 to May 2008 in Beijing Tian Hospital.Results Of the 53 cases(22 men,31 women),aged from 15 to 52(mean 34.92±9.69)years.Acute or sub-acme onset accounted mostly.The principal clinical characteristics were headache and vomit,weak sight,diplopia,focal deficit,conscious disturbance and seizures.The neuro-imaging findings of CVST were venous sinus occlusion and local infarction,sometimes accompanied by capillary hemorrhage or haematoma.The major treatment involve dehydration,anticoagulation,and thrombolysis or stent implanted.After the treatment,12 cases recovered completely,37 improved,2 invalided,and 2 cases discharged for herniation of brain.Conclusion Improvement in awareness of CVST and prompt MRI in combination with MRV examination is the key to accurate diagnosis and timely therapy.The treatment of CVST should be based on anticoagulatin,and acompanyed.by thrombolysis or stent implanted in cerebral venous sinus on the baisis of effect.