Effect of inferior hypothermy on serum TNF and IL-6 in patients with severe cerebral trauma / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 197-198, 2009.
Article
em Zh
| WPRIM
| ID: wpr-396143
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the effect of inferior hypothermy treatment on serum TNF and IL-6 in patients with severe cerebral trauma.Methods 46 patients were randomly divided into two groups:inferior hypothermy group(24 C88e8)and normal group(22 cases).There are the same basic treatments within the two groups,in the inferior hypothermy group we also sive them hypothermy treatment rectal temperature:32~34℃ which need to last for nearly 4~5 days,at the same time we give patients the lyric cocktail.the TNF,IL-6 and GCS grades on the lst and 14th day were tested.Results TNF and IL-6 as compared with normal group are higher than the inferior hypothermy group,the differences between the two groups are of statistical significance(P<0.01).The difference of GCS grades between the two groups are of stafictical significance(P<0.05).Conclusion The inferior hypothermy tbempy which inhibits TNF and IL-6 releasing after severe cerebral trauma and the following damages plays a very important role in the cerebral trauma therapy.
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WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Ano de publicação:
2009
Tipo de documento:
Article