Advance in relationship between translationally controlled tumor protein and tumor / 国际外科学杂志

ABSTRACT

Translationally controlled tumor protein(TCTP)is a highly conserved and homologous protein that is widely expressed in all eukaryotic organisms and regulated at both the transcriptional and the translational level. TCTP participates in the regadation of cell cycle and proliferation, anti-apoptosis, and tumor reversion in tumor; it also correlates with ehemo-resistance. It may become potential targets of anti-tumor therapy and tumor reversion and provides a novel ideal for cancer therapy.