Evaluation of pulmonary ventilation/perfusion imaging in monitoring thrombolytic therapy in pulmonary embolism / 中国综合临床

ABSTRACT

Objective To investigate the role of pulmonary ventilatioa/perfusion imaging in evaluating thrombolytic therapy in pulmonary embolism (PE).Methods Pulmonary ventilation/perfusion imagng was performed before and one week and three months after thrombolytic therapy in 43 patients with acute PE.Results Among 421 abnormal pulmonary segments in 43 PE cases,199(47.3%) and 231(54.9%) segments were restored to normal 1 week and 3 months later (P<0.05).Of two groups,more abnormal pulmonary segments were restored to normal in those with less than one week's onset (P<0.01).Conclusion As a non-invasive diagnostic method, pulmonary ventilation/perfusion imaging plays an important role in evaluating the therapeutic effectiveness of thrombolytic therapy in patients with PE.