Myocardial injury in 40 patients with dengue fever / 中华临床感染病杂志

ABSTRACT

Objective To investigate the myocardial injury in patients with dengue fever. Methods Three hundred and ninety-eight patients with dengue fever were included in the study. Blood myocardial enzyme spectrum and electrocardiography were examined in all patients. Results Abnormal myocardial enzyme spectrum was detected in 40 patients ( 10. 1% ), including the elevation of blood CK-MB, CK, LDH, α-HBDH and AST levels and increased cTnT levels were also detected in 5 patients. In these 40 patients, 34 showed abnormal electrocardiogram. Sinus bradycardia was the most common complication, other complications including ST or T wave changes. Some patients had more than two kinds of electrocardiogram abnormalities. Conclusion Dengue vires infection may induce myocardial injury, which suggests that examinations for myocardial enzyme spectrum and electrocardiography are necessary.