Recent advance in transplantation tolerance induced by apoptosis of T lymphocyte / 国际外科学杂志

ABSTRACT

Apoptosis is great advancement in sphere of biology,it is characteristic death form at physiological state.Rencent researchs discover that apoptosis take important role in transplantation immunity.That graft is rejected is the major obstruction in transplantation.Allogeneic transplantation rejection is because of immune response that is mediated by T lymphocyte and aimed directly at allogenic antigen.Apoptosis of activated T lymphocyte through some pathways can induce immune tolerance.Some immune suppressant produce effect just by cell apoptosis.This review mainly presents recent advance in transplantation tolerance induced by apoptosis of T lymphocyte.