Cutaneous Granulocytic Sarcoma: A report of two cases / 대한피부과학회지

ABSTRACT

Granulocytic sarcoma (GS), also known as chloroma, is an extramedullary tumor of granulocytic lineage. It usually occurs in patients with acute myelogenous leukemia (AML), myeloproliferative disorder, or myelodysplasia but can develop in patients with no known hematologic disorder (isolated chloroma). The sites of predilection are bone and periosteum, and the next most common sites are soft tissues of the skin, kidneys, gut and lymph nodes. We report herein two cases of GS in a 36 year-old male and a 39 year-old female. The former had been treated for AML for 4 months before GS developed as an exophytic and multiple cutaneous masses on his left arm. In the latter, whose chief complaint was plum-colored nodules on her trunk, the initial diagnosis was malignant lymphoma. A follow-up after chemotherapy revealed that she had AML and reversely the final diagnosis of GS could be made for her skin tumor.