Cancer stem cell and CD133 / 国际肿瘤学杂志
Journal of International Oncology
; (12): 326-329, 2008.
Article
em Zh
| WPRIM
| ID: wpr-400443
Biblioteca responsável:
WPRO
ABSTRACT
Recent evidence has increasedly supposed cancer stem cell theory.that cancers can be viewed as an abnormal organ in which tumor growth is driven by a population of cancer stem cells,with self-re-hewing and muti-differentiation potentiality.CD133 has been repofled sequentially in many malignan-cies.Although the biological function of CD133 is not well understood.the CD133 epitope cueeently senves as a useful marker for the isolation of cancer stem cells.Research has discovered that CD133+ tumor cells are in re-lation to tumorigenesis,invasion,metastasis,drug-resistance and recurrence.So,understanding the molecular bi-ology of the CD133+ tumor cells is essential for developing more effective anti-cancer tIeatments,especiallv tar-geting cancer stem cells.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2008
Tipo de documento:
Article