Nogo-A and Its Roles in Ischemic Cerebrovascular Disease / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 313-316, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-400701
ABSTRACT
Myelin-associated inhibitory factor is a major obstacle for axonal regeneration in the central nervous system, and Nogo-A is an important inhibiting factor synthesized by oligoden-drocytes. Toe expression levels of Nogo-A changed significantly in a model of ischemic cere-brovascular disease; the therapeutic measures aiming at Nogo-A and its downstream pathway can effectively enhance axonal regeneration, improve the plasticity of neural structure, and promote functional recovery. This provides a reliable theoretical basis for the development of therapeutic mode in human cerebrovascular diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
International Journal of Cerebrovascular Diseases
Ano de publicação:
2008
Tipo de documento:
Artigo
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