Rho/ROCK and Neurological Diseases / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 233-236, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-401331
ABSTRACT
As a molecular switch,Rho can be transformed between the inactive GDP-bound form and the active GTP-bound form,transfering signals to downstream effector Rho kinase (ROCK),mediating specific biological effects,and participating in various neurological diseases, such as the pathological processes of ischemic stroke,cerebral vasospasm,and axonal regeneration after spinal cord injury.The application of ROCK inhibitor in the treatment of neurological diseases has achieved satisfactory effect.Rho/ROCK is expected to become a novel therapeutic target.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Cerebrovascular Diseases
Ano de publicação:
2008
Tipo de documento:
Artigo
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