Preparation of small-caliber expanded poly(tetrafluoroethylene) vascular grafts applied by silk fibroin film with surface sulfonation by low temperature plasma treatment / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 1357-1360, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-402815
ABSTRACT
BACKGROUND:
Silk fibroin film showed an anti-coagulated blood activity following sulfurous acid treatment; however, its flexibility and anti-tension were poor. If the silk flbroin film was coated on small-caliber expanded poly(tetrafiuoroethylene) (ePTFE) vascular grafts prior to surface sulfonation, the adverse effects were improved and the blood compatibility of ePTFE vascular grafts were remarkably enhanced.OBJECTIVE:
To research the preparation of ePTFE vascular grafts applied by surface sulfonation of silk flbroin film by low temperature plasma treatment.METHODS:
The ePTFE vascular grafts were treated with low temperature plasma and coated on the surface of silk fibroin. The compound was then sulfonated with low temperature plasma. The ePTFE vascular grafts were considered as the controls to detect contact angle and sulfonation. RESULTS ANDCONCLUSION:
The contact angle was decreased gradually form 87.7°to 65.1° following low temperature plasma treatment. Moreover, the contact angle was 106.2° following coating silk flbroin film and 92.9°following sulfonation. X-raylight-electron spectrometer demonstrated that percents of sulfur element on the surfaces of the combined blood vessel was 2.89%, respectively, while that of the control film was only 0.12%. The X-ray light-electron spectrometer also showed that most of the sulfur element were sulfonic group (-SO_3H). The results suggested the feasibility of the preparation of the combined blood vessel.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Tissue Engineering Research
Ano de publicação:
2010
Tipo de documento:
Artigo
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