Investigation of pulse pressure and related factors of 1989 healthy adults in Sichuan province / 中国组织工程研究

ABSTRACT

BACKGROUND:High pulse pressure is the signal of arteriosclerosis or cardiovascular diseases for both hypertension and normal blood pressure population.OBJECTIVE:The pulse pressure and related factors of healthy adults in Sichuan province were analyzed to explore the method for preventing excessive pulse pressure and improving the quailty of life.METHODS:Hierarchical,cluster sampling were performed in 1989 healthy adults.The physical examination,blood glucose,renal function and blood fat were detected,and the relation of pulse pressure and its related factors were analyzed.RESULTS AND CONCLUSION:Pulse pressure increased following the age.especially showed a linear increasing in those who more than 50-year-old The increased pulse pressure leaded to larger fasting plasma glucose,uric acid,blood urea nitrogen,total cholesterol,triacylglycerol,systolic pressure and diastolic pressure,in addition,the age,body mass index,waist-to-hip ratio,triacylglycerol and pulse pressure showed a linear relationship.But physical exercise was negative correlated to pulse pressure.With pulse pressure increasing,the renal function and regulating capacity of blood glucose was decreased The results suggested that mid-aged population should take reasonable diet and more physical exercise to prevent central obesity and excessive pulse pressure,reduce the risk of renal dysfunction and the incidence of cardiovascular disease.