The high mobility group protein A2 and tumor / 中国癌症杂志
China Oncology
;
(12): 156-160, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-403659
ABSTRACT
The high mobility group A2 (HMGA2), one ofnon-histone chromatin proteins, may alter chromatin structure and thereby regulate the transcription of several genes by either enhancing or suppressing transcription factors, and leading to malignant neoplasm formation. This paper focuses on the role of the HMGA proteins in human neoplastic diseases, and discusses the mechanisms by which they contribute to carcinogenesis, and diagnosis strategies based on targeting HMGA proteins.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
China Oncology
Ano de publicação:
2010
Tipo de documento:
Artigo
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