Research progress in prorenin and prorenin receptor / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12): 405-408, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-403921
ABSTRACT
The renin-angiotension system (RAS) plays an important role in cardiovascular and renal physiology and diseases. Recent discoveries of prorenin and prorenin receptor add new contents to RAS. Renin and prorenin binding to the prorenin receptor not only target and facilitate angiotensin generation but also lead to activation of prorenin receptor signal transduction pathways, which is distinct from classical RAS signaling. In this paper, the construction, function and signal trasduction of prorenin, prorenin receptor and handle region peptide are reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
2010
Tipo de documento:
Artigo
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